Tim Mant Selected Research

fitusiran

1/2021	Targeting of antithrombin in hemophilia A or B with investigational siRNA therapeutic fitusiran-Results of the phase 1 inhibitor cohort.
1/2017	Targeting of Antithrombin in Hemophilia A or B with RNAi Therapy.

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Tim Mant Research Topics

Disease

3	Hemophilia A (Haemophilia) 01/2021 - 08/2015
2	Hemorrhage 01/2021 - 08/2015
2	Rheumatoid Arthritis 12/2017 - 07/2013
2	Body Weight (Weight, Body) 01/2017 - 10/2015
2	Pulmonary Arterial Hypertension 05/2016 - 06/2015
1	Spinal Cord Injuries (Spinal Cord Injury) 12/2023
1	Exanthema (Rash) 12/2023
1	Eye Diseases (Eye Disease) 12/2023
1	Experimental Arthritis 01/2017
1	Autoimmune Diseases (Autoimmune Disease) 01/2017
1	Neoplasms (Cancer) 01/2017
1	Heart Failure 12/2015
1	Chronic Pain 10/2015
1	Hyperesthesia 10/2015
1	Osteoarthritis 10/2015
1	Pain (Aches) 10/2015
1	Paresthesia (Dysesthesia) 10/2015
1	Knee Osteoarthritis 10/2015
1	Human Influenza (Influenza) 04/2009
1	Respiratory Tract Infections (Respiratory Tract Infection) 04/2009
1	Infections 04/2009
1	Fever (Fevers) 04/2009
1	Exercise-Induced Asthma (Asthma, Exercise Induced) 05/2002

Drug/Important Bio-Agent (IBA)

2	AntithrombinsIBA 01/2021 - 01/2017
2	fitusiranIBA 01/2021 - 01/2017
2	Syk KinaseIBA 01/2017 - 07/2013
1	Retinoic Acid Receptors (Retinoic Acid Receptor)IBA 12/2023
1	EnzymesIBA 12/2023
1	Small Interfering RNA (siRNA)IBA 01/2021
1	IsoantibodiesIBA 01/2017
1	4- (3- (2H- 1,2,3- triazol- 2- yl)phenylamino)- 2- (2- aminocyclohexylamino)pyrimidine- 5- carboxamideIBA 01/2017
1	Blood Coagulation Factors (Coagulation Factor)IBA 01/2017
1	Thrombin FDA Link 01/2017
1	Hemostatics (Antihemorrhagics)IBA 01/2017
1	selexipagIBA 05/2016
1	Epoprostenol ReceptorsIBA 05/2016
1	Warfarin (Coumadin)FDA LinkGeneric 05/2016
1	Digoxin (Digitek)FDA LinkGeneric 12/2015
1	Monoclonal AntibodiesIBA 10/2015
1	Nerve Growth Factor (NGF)IBA 10/2015
1	AMG 403IBA 10/2015
1	Factor VIII (Coagulation Factor VIII)IBA 08/2015
1	BAX 855IBA 08/2015
1	Epoprostenol (Prostacyclin)FDA LinkGeneric 06/2015
1	ProdrugsIBA 07/2013
1	fostamatinibIBA 07/2013
1	DNA VaccinesIBA 04/2009
1	VaccinesIBA 04/2009
1	DNA (Deoxyribonucleic Acid)IBA 04/2009
1	Albuterol (Salbutamol)FDA LinkGeneric 05/2002

Therapy/Procedure

2	Subcutaneous Injections 01/2021 - 01/2017
1	Therapeutics 01/2021
1	Polypharmacy 12/2017
1	Intravenous Infusions 01/2017
1	RNAi Therapeutics 01/2017
1	Injections 01/2017